Please use this identifier to cite or link to this item: http://hdl.handle.net/10625/48022
Title: Cognitive impairment in an adult Mexican population non-occupationally exposed to manganese
Authors: Solís-Vivanco, Rodolfo
Rodríguez-Agudelo, Yaneth
Riojas-Rodríguez, Horacio
Ríos, Camilo
Rosas, Irma
Montes, Sergio
Keywords: NEUROCOGNITIVE FUNCTIONS
MANGANESE
NEUROTOXICITY
ATTENTION IMPAIRMENT
NEUROBEHAVIOURAL ASSESSMENT
AIR POLLUTION
MEXICO
MANAGES MINING
RISK ASSESSMENT
HAIR MANGANESE LEVELS
BLOOD MANGANESE LEVELS
MILD COGNITIVE IMPAIRMENT
Date: 2009
Publisher: Elsevier
Abstract: We examined the association between non-occupational exposure to Mn and cognitive functions. The studywas carried out in a mining district located in Hidalgo State, Mexico, with 288 adults. Air and blood Mn concentrations were determined, and neuropsychological tests were administered to explore cognitive functions and depression. Blood Mn mean was 9.5±4.14 g/L. A total of 73% of the study group were in contact with air Mn levels that surpassed the EPA recommended guideline level for non-occupational environments (0.05 g/m3). AirMnconcentrationwas associated as a risk factor for attention impairment (OR = 1.75, 95% CI: 1.01–3.06). Blood Mn levelswere not associated to any of the measured outcomes. The main finding of this study is the presence of attention impairments associated to high levels of air Mn exposure. These results confirm previous studies, in which cognitive impairment is reported for exposed population.
URI: http://hdl.handle.net/10625/48022
Project Number: 103052
Project Title: Manganese Exposure in the General Population in a Mining District (Mexico) - Phase II
Access: IDRC Only
Files in This Item:
File Description SizeFormat 
IDL-48022.pdf211.19 kBAdobe PDFView / IDRC staff only    Request a copy
Show full item record